NAD+

Fact sheet summary

What it is

NAD+ stands for nicotinamide adenine dinucleotide. It is a coenzyme, not a peptide. Cells use it in energy metabolism, DNA repair and signalling. These normal biological roles do not prove benefits from taking extra NAD+.

Know the difference

NMN and NR are building blocks the body can use to make NAD+. Oral supplements and intravenous NAD+ infusions are different interventions; their evidence is not interchangeable.

Reported benefits and women’s research

More energy, clearer thinking and healthy ageing are commonly promoted benefits. The sheet describes limited clinical evidence for NAD+ infusions and a small oral NMN study in postmenopausal women with prediabetes. That study does not establish benefits of NAD+ infusions or treatment of menopause symptoms.

Australian guidance and safety

The TGA distinguishes NAD+, NADH and NMN when describing ingredients permitted in listed medicines. Check the exact product and its ARTG entry with a pharmacist or GP. The sheet notes infusion side effects and uncertainty about long-term safety.

This summary accompanies the supplied fact sheet. General information, not individual medical advice. Our editorial standards.